Cart
sales@molnova.com
Proadrenomedullin (1-20), human
CAS No. 150238-87-2
Proadrenomedullin (1-20), human( —— )
Catalog No. M30189 CAS No. 150238-87-2
Endogenous peptide agonist of Mas related GPR X2 (MRGPRX2, EC50 = 251 nM). Also a noncompetitive nicotinic cholinergic antagonist. Inhibits nicotine-stimulated catecholamine secretion from PC12 cells in vitro, and from sympathetic nerve endings and adrenal chromaffin cells in vivo. Corresponds to amino acids 1 - 20 of proadrenomedullin. Antihypertensive.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 100MG | Get Quote | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
Biological Information
-
Product NameProadrenomedullin (1-20), human
-
NoteResearch use only, not for human use.
-
Brief DescriptionEndogenous peptide agonist of Mas related GPR X2 (MRGPRX2, EC50 = 251 nM). Also a noncompetitive nicotinic cholinergic antagonist. Inhibits nicotine-stimulated catecholamine secretion from PC12 cells in vitro, and from sympathetic nerve endings and adrenal chromaffin cells in vivo. Corresponds to amino acids 1 - 20 of proadrenomedullin. Antihypertensive.
-
DescriptionEndogenous peptide agonist of Mas related GPR X2 (MRGPRX2, EC50 = 251 nM). Also a noncompetitive nicotinic cholinergic antagonist. Inhibits nicotine-stimulated catecholamine secretion from PC12 cells in vitro, and from sympathetic nerve endings and adrenal chromaffin cells in vivo. Corresponds to amino acids 1 - 20 of proadrenomedullin. Antihypertensive.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayOthers
-
TargetOther Targets
-
Recptor——
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number150238-87-2
-
Formula Weight2460.84
-
Molecular FormulaC112H178N36O27
-
Purity>98% (HPLC)
-
Solubility——
-
SMILES——
-
Chemical NameSequence:{Ala}{Arg}{Leu}{Asp}{Val}{Ala}{Ser}{Glu}{Phe}{Arg}{Lys}{Lys}{Trp}{Asn}{Lys}{Trp}{Ala}{Leu}{Ser}{Arg}-NH2
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
Mahata M, et al. Proadrenomedullin N-terminal 20 peptide: minimal active region to regulate nicotinic receptors. Hypertension. 1998 Nov;32(5):907-16.
molnova catalog
related products
-
Acecainide hydrochlo...
Acecainide hydrochloride is a major metabolite of procainamide. Its anti-arrhythmic action may cause cardiac toxicity in kidney failure.
-
3-hydroxy-3-phenylpe...
3-hydroxy-3-phenylpentanamide is a chemical compound.
-
Kalopanaxsaponin H
Macranthoside A is a triterpenoid glycoside extracted from rehmannia and belongs to the iridoterpenoid synthesis.
