Proadrenomedullin (1-20), human( —— )

Catalog No. M30189 CAS No. 150238-87-2

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Product Name

Proadrenomedullin (1-20), human
Note

Research use only, not for human use.
Brief Description

Endogenous peptide agonist of Mas related GPR X2 (MRGPRX2, EC50 = 251 nM). Also a noncompetitive nicotinic cholinergic antagonist. Inhibits nicotine-stimulated catecholamine secretion from PC12 cells in vitro, and from sympathetic nerve endings and adrenal chromaffin cells in vivo. Corresponds to amino acids 1 - 20 of proadrenomedullin. Antihypertensive.
Description

Endogenous peptide agonist of Mas related GPR X2 (MRGPRX2, EC50 = 251 nM). Also a noncompetitive nicotinic cholinergic antagonist. Inhibits nicotine-stimulated catecholamine secretion from PC12 cells in vitro, and from sympathetic nerve endings and adrenal chromaffin cells in vivo. Corresponds to amino acids 1 - 20 of proadrenomedullin. Antihypertensive.
In Vitro

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In Vivo

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Synonyms

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Pathway

Others
Target

Other Targets
Recptor

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Research Area

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Indication

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CAS Number

150238-87-2
Formula Weight

2460.84
Molecular Formula

C112H178N36O27
Purity

>98% (HPLC)
Solubility

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SMILES

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Chemical Name

Sequence:{Ala}{Arg}{Leu}{Asp}{Val}{Ala}{Ser}{Glu}{Phe}{Arg}{Lys}{Lys}{Trp}{Asn}{Lys}{Trp}{Ala}{Leu}{Ser}{Arg}-NH2